Cisco Cisco Systems This document defines a protocol abstraction layer that enables Media over QUIC Transport (MOQT) to serve as a unified transport substrate for inter-agent communication protocols. The abstraction provides a common mapping of request-response and streaming patterns onto MOQT's publish/subscribe model, allowing diverse agent protocols to leverage MOQT's real-time streaming capabilities, built-in prioritization, and efficient multiplexing over QUIC. The document demonstrates the application of this abstraction to two prominent inter-agent protocols: the Agent-to-Agent (A2A) protocol [A2A], which focuses on agent discovery, task delegation, and collaboration; and the Model Context Protocol (MCP) [MCP], which provides tool and resource access for agents. This unified approach enables interoperability across diverse agent ecosystems while preserving each protocol's semantics.